Differential expression of secreted factors <i> <scp>SOSTDC</scp> 1 </i> and <i> <scp>ADAMTS</scp> 8 </i> cause profibrotic changes in linear morphoea fibroblasts

Abstract

We demonstrate that cell-intrinsic changes in the LM fibroblast secretome lead to changes observed in the disease, and that secretome modulation could be a viable therapeutic approach in the treatment of LM.