Advances in Radiation Oncology · 2019 · 51 citations · 33 references
MedicineOncologyRadiation OncologyBreast Radiation OncologyCardio-oncologyClinical Radiation OncologyBreast Cancer RadiotherapyBreast Radiation CareBreast-conserving TherapyDeep Inspiration Breath HoldRadiation TherapyRadiation Treatment PlanningBreath-hold RadiotherapyCardiac Dose ReductionCardiac Radiation DosimetryDescriptive Statistics TablesInstitutional Review Board ApprovalRadiation Exposure Management
PURPOSE: Radiation dose to the heart correlates with cardiac-related deaths and may partially diminish the benefit of radiation for breast cancer. This study assessed the current nationwide trends in heart-sparing techniques for breast cancer radiation. METHODS AND MATERIALS: tests. RESULTS: < .01). Seventy-three percent of physicians used heart-sparing techniques for more than three-fourths of left-sided patients. The most commonly used technique was DIBH, and 43% of physicians used the technique more than three-fourths of the time. Commonly used DIBH systems were Varian RPM (54%) and Vision RT/Align RT (31%). No increase in DIBH use was observed with regional nodal irradiation, and coverage of internal mammary chain nodes varied. Patient tolerance (78%) and cardiac-to-chest wall distance (72%) were the most common determinants of DIBH in left-sided patients. Twenty-three percent of physicians used DIBH for right-sided patients, with lung (64%) and heart sparing (46%) as the most common reasons for use. Lack of facilities was the most common reason not to use DIBH (61%). CONCLUSIONS: Most respondents offer heart-sparing techniques for breast cancer radiation; this is more common in academic centers. DIBH is the most common technique across all practice settings. DIBH is much less commonly used in right-sided patients but is still used by >20% of practitioners, with lung and heart sparing cited as reasons for use. More data are needed to determine if and when this technique should be used in right-sided cases.
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Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer
Sarah C. Darby, Marianne Ewertz, Paul McGale et al. · New England Journal of Medicine · 2013 · 4K citations · Full text
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Regional Nodal Irradiation in Early-Stage Breast Cancer
Timothy J. Whelan, Ivo A. Olivotto, Wendy R. Parulekar et al. · New England Journal of Medicine · 2015 · 1.3K citations · Full text
Sarah C. Darby, Paul McGale, Carolyn Taylor et al. · The Lancet Oncology · 2005 · 1K citations