Publication | Closed Access
Application of Hantzsch Ester and Meyer Nitrile in Radical Alkynylation Reactions
36
Citations
52
References
2018
Year
The first example of constructing a C<sub>sp3</sub>-C<sub>sp</sub> bond with substituted Hantzsch ester and Meyer nitrile is reported. When benziodoxole-activated alkyne was applied as the alkynyl donor, products containing C<sub>sp3</sub>-C<sub>sp</sub> bonds involving primary, secondary, and tertiary carbon centers were achieved in up to 97% yields. K<sub>2</sub>S<sub>2</sub>O<sub>8</sub> was the optimum radical initiator in this reaction.
| Year | Citations | |
|---|---|---|
Page 1
Page 1