Complex Congenital Heart Disease Associated With Disordered Myocardial Architecture in a Midtrimester Human Fetus

Abstract

We have shown the potential of X-ray phase-contrast imaging for studying cardiac microstructure in the developing human fetal heart at high resolution providing novel insight while preserving valuable archival material for future study. This is the first study to show myocardial alterations occur in complex CHD as early as midgestation.