DIPEAc promoted one-pot synthesis of dihydropyrido[2,3-<i>d</i>:6,5-<i>d</i>′]dipyrimidinetetraone and pyrimido[4,5-<i>d</i>]pyrimidine derivatives as potent tyrosinase inhibitors and anticancer agents: <i>in vitro</i> screening, molecular docking and ADMET predictions

Abstract

Efficient and rapid synthesis of 18 tyrosinase inhibitors with good to moderate anticancer activity and good oral drug like properties.