Combined diffusion‐relaxometry MRI to identify dysfunction in the human placenta

Abstract

Combined <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msubsup><mml:mtext>T</mml:mtext><mml:mn>2</mml:mn><mml:mo>*</mml:mo></mml:msubsup></mml:math> -diffusivity MRI is promising for assessing fetal and maternal health during pregnancy. The <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msubsup><mml:mtext>T</mml:mtext><mml:mn>2</mml:mn><mml:mo>*</mml:mo></mml:msubsup></mml:math> -ADC spectrum potentially provides additional information on tissue microstructure, compared to measuring these two contrasts separately. The presented method is immediately applicable to the study of other organs.