Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways

Abstract

In normal/healthy human airways, MUC5B is the dominant secretory mucin in the superficial epithelium and glands, with distal airways being a major site of expression. MUC5B and MUC5AC expression is a property of CCSP-positive secretory cells in superficial airway epithelia.