Biomedical Optics Express · 2018 · 158 citations · 34 references
ComputingComputer ScienceOral PathologyBiomedical ImagingComputer VisionMachine LearningDeep LearningImage Feature EngineeringOral Cancer PathologyOral Cavity CancerOral Disease DiagnosticsOral Potentially Malignant DisordersAutomatic ClassificationConvolutional Neural NetworksDeep Learning-based ClassificationDeep Learning-based Image FusionDeep Learning-based Lesion ClassificationMulti-modal Cancer DetectionRegularizationRegularization Techniques
With the goal to screen high-risk populations for oral cancer in low- and middle-income countries (LMICs), we have developed a low-cost, portable, easy to use smartphone-based intraoral dual-modality imaging platform. In this paper we present an image classification approach based on autofluorescence and white light images using deep learning methods. The information from the autofluorescence and white light image pair is extracted, calculated, and fused to feed the deep learning neural networks. We have investigated and compared the performance of different convolutional neural networks, transfer learning, and several regularization techniques for oral cancer classification. Our experimental results demonstrate the effectiveness of deep learning methods in classifying dual-modal images for oral cancer detection.
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