PubMed · 2019 · 30 citations · 17 references
Open access
PharmacyPediatricsPharmacotherapyPediatric Clinical PharmacologyPediatric PharmacotherapyPediatric TherapeuticsAsthma ManagementAsthma PharmacotherapyRespiratory MedicineAdministration Of Herbal RemediesChildhood Asthma ManagementCommon ColdHerbal SupplementsPeak Expiratory Flow ResponsePediatric Asthma PharmacotherapyTraditional Herbal FormulationsTraditional Herbal Medicine
OBJECTIVE: ) in asthmatic children during viral respiratory tract infection, were evaluated. MATERIALS AND METHODS: ) or placebo for 5 days. Primary outcomes included day symptoms, night symptoms, and asthma attacks. Secondary outcomes included Peak Expiratory Flow Rate (PEFR), the need for β-agonist administration, oral prednisolone usage, necessity for re-visit due to uncontrolled or insupportable symptoms, as well as the number of hospital admissions and days absent from school. RESULTS: the herbal mixture significantly decreased the severity of coughs (p=0.049) and nighttime awakenings (p=0.029) in comparison to placebo. There was no significant reduction in wheezing, tachypnea, respiratory distress, PEF rate, absence from school, outpatient visits, asthma exacerbation, oral prednisolone or β-agonist usage and hospitalization. CONCLUSION: Short-course of herbal mixture this traditional herbal mixture, starting at the onset of signs of a viral respiratory tract infection in children with intermittent asthma, reduced cough and nights awakening. Further studies should be done to determine the most effective herbal admixture, as well as dose and duration of treatment.
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