Dupilumab in the management of topical corticosteroid withdrawal in atopic dermatitis: A retrospective case series

Abstract

Topical corticosteroid (TCS) withdrawal, or steroid addiction, is a poorly understood, distinct adverse effect of inappropriate TCS use. It occurs most commonly in adult women applying mid- or high-potency TCS to the face or genital region and is associated with increased frequency and duration of treatment.1-3 TCS withdrawal should be suspected when confluent erythema appears within days to weeks of discontinuing therapy, stinging and burning are prominent symptoms, and history is consistent with the at-risk population described above.