Concepedia

Cross-talk among writers, readers, and erasers of m <sup>6</sup> A regulates cancer growth and progression

Panneerdoss Subbarayalu, Vijay Kumar Eedunuri, Pooja Yadav, Santosh Timilsina, Subapriya Rajamanickam, Suryavathi Viswanadhapalli, Nourhan Abdelfattah, Benjamin Onyeagucha, Xiaodong Cui, Zhao Lai,

Science Advances · 2018 · 364 citations · 35 references

DOIFull text

Open access

Concepts

Abstract

A threshold, leading to uncontrolled expression/activity of those genes, resulting in tumor growth, angiogenesis, and progression.

References

35

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Dan Dominissini, Sharon Moshitch-Moshkovitz, Schraga Schwartz et al. · Nature · 2012 · 5K citations

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N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

Guifang Jia, Ye Fu, Xu Zhao et al. · Nature Chemical Biology · 2011 · 4.1K citations

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A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

Jianzhao Liu, Yanan Yue, Dali Han et al. · Nature Chemical Biology · 2013 · 3.5K citations · Full text

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Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

Xiaoli Ping, Baofa Sun, Lu Wang et al. · Cell Research · 2014 · 2.4K citations · Full text

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5′ UTR m6A Promotes Cap-Independent Translation

Kate D. Meyer, Deepak P. Patil, Jun Zhou et al. · Cell · 2015 · 1.8K citations · Full text

, , +14