Concepedia

Publication | Open Access

A sheep model of cystic fibrosis generated by CRISPR/Cas9 disruption of the CFTR gene

DOIFull Paper Access

129

Citations

32

References

2018

Year

Zhiqiang Fan, Iuri Viótti Périssé, Calvin U. Cotton, Misha Regouski, Qinggang Meng, Chaim Domb, Arnaud J. Van Wettere, Zhongde Wang, Ann Harris, Kenneth L. White,
JCI Insight

Abstract

Eight twin pregnancies were obtained (4 in CFTR -/-and 4 in CFTR +/-groups). ** Two CFTR +/-lambs were euthanized due to broken ribs resulting from accidental injuries. Values in the same column with different superscript letters differ significantly (P < 0.05, 2 test).

References

YearCitations

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