Organometallics · 2018 · 318 citations · 56 references
Natural SciencesChemical EngineeringChemistryCatalysisIndustrial ChemistryPharmaceutical ManufacturingCatalyst DesignCatalyst SynthesisGreen CatalysisIndustrial CatalysisIndustrial Catalytic ProcessesMetal CatalysisCatalyst Development For SynthesisCatalytic Process OptimizationEnvironmental CatalysisMetal-based CatalysisMetallosupramolecular CatalysisSustainable Reaction EngineeringSustainable SynthesisTransition Metal-catalyzed Synthesis
As companies grow ever more mindful of the sustainability aspects of their products and supply chains, an increasing focus on the environmental impact of pharmaceutical manufacture spurs innovation from chemists who support this industry. Metal catalysis has the potential to greatly enhance the sustainability of pharmaceutical products, leading to shorter and more efficient synthetic routes and more direct access to single stereoisomeric products. This perspective article seeks to highlight a number of important considerations for the design of new and improved sustainable metal-catalyzed transformations in order to facilitate rapid adoption by the pharmaceutical industry.
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CHEM21 selection guide of classical- and less classical-solvents
Denis Prat, A.S. Wells, John Hayler et al. · Green Chemistry · 2015 · 2.1K citations · Full text