Novel biomarker signatures for idiopathic REM sleep behavior disorder

Stefania Mondello, Firas Kobeissy, Yehia Mechref, Jingfu Zhao, Farid Talih, F. Cosentino, Elena Antelmi, Monica Moresco, Giuseppe Plazzi, Raffaele Ferri

Neurology · 2018 · 31 citations · 8 references

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Abstract

Our results shed light on the protein signature profile, molecular pathways, and mechanisms involved in the pathogenesis of RBD and its clinical manifestation. This knowledge opens a new avenue towards more accurate and timely diagnosis and characterization of RBD, which might ultimately translate into new therapeutic strategies with disease-modifying effects. Further evaluation of the identified markers is required to confirm their diagnostic value and potential to guide clinical decision-making.

References

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