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Exploiting a conjugative CRISPR/Cas9 system to eliminate plasmid harbouring the mcr-1 gene from Escherichia coli

Conjugative Crispr/cas9 SystemMcr-1 GeneGenetic EngineeringMolecular BiologyEscherichia ColiMolecular GeneticsGene EditingCrisprMicrobiologyOff-target EffectMedicineGenome EditingMicrobial Genetics