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High Rate of Ceftobiprole Resistance among Clinical Methicillin-Resistant <i>Staphylococcus aureus</i> Isolates from a Hospital in Central Italy

Gianluca Morroni, Andrea Brenciani, Lucia Brescini, Simona Fioriti, Serena Simoni, Antonella Pocognoli, Marina Mingoia, Eleonora Giovanetti, Francesco Barchiesi, Andrea Giacometti,

Antimicrobial Agents and Chemotherapy · 2018 · 31 citations · 16 references

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Abstract

Ceftobiprole is a fifth-generation cephalosporin with activity against methicillin-resistant Staphylococcus aureus (MRSA). One-year surveillance at the Regional Hospital of Ancona (Italy) disclosed a 12% ceftobiprole resistance rate (12/102 isolates; MIC, ≥4 mg/liter).

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