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Investigation of an increase in large local reactions following vaccine schedule change to include DTaP-HB-IPV-Hib (Infanrix-hexa®) and MMRV (ProQuad®) at 18 months of age

VaccinationVaccine SafetyLarge Local ReactionsAllergyVaccine DevelopmentImmunologyHumoral ImmunityVaccine EfficacyMedicineVaccine ResearchVaccine Schedule Change