Anti-beta2 glycoprotein I and anticardiolipin antibodies in leptospirosis, syphilis and Kala-azar.

M. Santiago, Reinaldo Martinelli, Albert I. Ko, Edna Afonso Reis, Roberto Dias Fontes, Eliane G. Nascimento, Silvia S. Pierangeli, Ricardo Espinola, A E Gharavi

PubMed · 2001 · 59 citations · 0 references

Abstract

This study clearly shows a significant prevalence of anti-beta2GPI antibodies in leptospirosis and leishmaniasis and syphilis. This indicates that the assay for antibeta2GPI antibodies should be thoroughly validated before it is introduced as a definitive tool for the diagnosis of APS, testing a larger number of sera from patients with a wider range of clinical conditions.