Mangosteen peel extract (<i>Garcinia mangostana</i> L.) as protective agent in glucose-induced mesangial cell as <i>in vitro</i> model of diabetic glomerulosclerosis.

Abstract

MPE can increase cell proliferation in glucose-induced mesangial cells and significantly reduce the level of TGF-β1 and fibronectin. MPE activity has correlates to inhibit the diabetic glomerulosclerosis condition and may increase mesangial cell proliferation.