Sipakmed: A New Dataset for Feature and Image Based Classification of Normal and Pathological Cervical Cells in Pap Smear Images

Abstract

Classification of cervical cells in Pap smear images is a challenging task due to the limitations these images exhibit and the complexity of the morphological changes in the structural parts of the cells. This procedure is very important as it provides fundamental information for the detection of cancerous or precancerous lesions. For this reason several algorithms have been proposed in order to classify normal and abnormal cells in such images. However, it is a common phenomenon that each research group usually creates its own dataset of images, as well-established datasets are not publicly available. To overcome this obstacle and to assist the research progress in this field, we present an annotated image database of Pap smear images, in which the cells are categorized in five different classes, depending on their cytomorphological features. The area of the cytoplasm and the nucleus in each image is manually defined by experts and salient features of intensity, texture and shape are calculated for each region of interest. Several experiments have been performed for the classification of these images and they include feature and image based classification schemes. In this direction, methods based on support vector machines and deep neural networks are tested and the performance of each classifier is presented in order to constitute a reference point for the evaluation of future classification techniques.