Molecular Therapy · 2018 · 61 citations · 55 references
Life SciencesGeneticsMolecular BiologyGene TherapyGenetic EngineeringGenome EditingCrispr-based EngineeringCrispr-cas SystemsRna EditingTherapeutic Genome EditingClustered Regularly Interspaced Short Palindromic Repeats (Crispr)-based MutagenesisCrispr-cas Genome EditingCrispr-cas9 Genome EditingEditing For Muscular DystrophyGene DeletionPolyadenylationRepeat Expansion MutationsTargeted Gene Insertion
55
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell · 2007 · 20.2K citations
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al. · Science · 2007 · 10.3K citations
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin et al. · Cell · 2013 · 3.4K citations · Full text