Concepedia

Publication | Open Access

Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration

DOIFull Paper Access

63

Citations

49

References

2018

Year

Johnny Di Pierdomenico, Rebecca Scholz, Francisco J. Valiente‐Soriano, M.C. Sánchez-Migallón, Manuel Vidal‐Sanz, Thomas Langmann, Marta Agudo‐Barriuso, Diego García‐Ayuso, María Paz Villegas‐Pérez
Investigative Ophthalmology & Visual Science

Abstract

In two animal models of photoreceptor degeneration with different etiologies, minocycline reduces microglial activation and migration, and FGF2 and minocycline increase photoreceptor survival. The combination of FGF2 and minocycline show greater neuroprotective effects than their isolated effects.

References

YearCitations

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