Concepedia

Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes

Gemma Navarro, Irene Reyes‐Resina, Rafael Rivas‐Santisteban, Verónica Sánchez de Medina, Paula Morales, S. Casano, Carlos Ferreiro‐Vera, Alejandro Lillo, David Aguinaga, Nadine Jagerovic,

Biochemical Pharmacology · 2018 · 95 citations · 35 references

DOI

Concepts

References

35

The 2.6 Angstrom Crystal Structure of a Human A <sub>2A</sub> Adenosine Receptor Bound to an Antagonist

Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson et al. · Science · 2008 · 1.8K citations · Full text

, , +17

Operational models of pharmacological agonism

J.W. Black, P. Leff · Proceedings of the Royal Society of London. Series B, Biological sciences · 1983 · 1.1K citations

, , +16

Cannabidiol is a negative allosteric modulator of the cannabinoid CB <sub>1</sub> receptor

Robert B. Laprairie, Amina M. Bagher, Michael E. Kelly et al. · British Journal of Pharmacology · 2015 · 1K citations · Full text

, , +13

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

Christian C. Felder, Kelly E. Joyce, Eileen M. Briley et al. · Molecular Pharmacology · 1995 · 879 citations

, , +7

Agonistic Properties of Cannabidiol at 5-HT1a Receptors

Ethan B. Russo, Andrea Burnett, Brian Hall et al. · Neurochemical Research · 2005 · 877 citations

, , +14