Sitagliptin attenuates intestinal ischemia/reperfusion injury via cAMP/PKA, PI3K/Akt pathway in a glucagon-like peptide 1 receptor-dependent manner

Intestinal Mucosal Lesion in Low-Flow States

Chu-Jeng Chiu · Archives of Surgery · 1970 · 1.8K citations

Life Sciences, Pathology, Physiology +17

Apoptosis is a major mode of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium

Hiroshi Ikeda, Yasuhiko Suzuki, Minako Suzuki et al. · Gut · 1998 · 320 citations · Full text

Veterinary Medicine, Cell Biology, Pathology +14

GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R

Bernardo Yusta, Laurie L. Baggio, Jacqueline A. Koehler et al. · Diabetes · 2015 · 271 citations

Life Sciences, Endocrinology, Immunology +17

Dipeptidyl Peptidase 4 Inhibitor Sitagliptin Protects Endothelial Function in Hypertension Through a Glucagon–Like Peptide 1–Dependent Mechanism

Limei Liu, Jian Liu, Wing Tak Wong et al. · Hypertension · 2012 · 180 citations · Full text

Medicine, Endocrinology, Pharmacology +17

The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways

Huili Zhu, Yusheng Zhang, Zhongshan Shi et al. · Scientific Reports · 2016 · 180 citations · Full text

Medicine, Neuroscience, Pharmacology +17