Zoledronate inhibits fibroblasts’ proliferation and activation via targeting TGF-β signaling pathway

Zichang Zhao, Wei Shen, Hanbin Zhu, Lin Lin, Gening Jiang, Yongzhe Zhu, Hongyuan Song, Liang Wu

Drug Design Development and Therapy · 2018 · 16 citations · 21 references

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Abstract

Our findings demonstrated that zoledronate can inhibit the proliferation, migration and activation of fibroblasts via the TGF-β signaling pathway and revealed a novel mechanism of zoledronate action against neointimal hyperplasia.

References

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