Outbreak of Hypervirulent Multidrug-resistant<i>Klebsiella variicola</i>Causing High Mortality in Neonates in Bangladesh

Abstract

We report a clonal outbreak of multidrug-resistant (MDR) Klebsiella variicola (sequence type [ST] 771) in a Bangladeshi neonatal unit from October 2016 to January 2017, associated with high mortality (54.5%). During the outbreak, K. variicola ST771 acquired an MDR plasmid harboring blaNDM-1, linked to high exposure to ceftriaxone and amikacin.