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NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia

Hematological MalignancyGenetic DisorderMedicineHematologyPathologyThiopurine MetabolismCancer GeneticsNt5c2 Relapse MutationsMolecular DiagnosticsRadiation OncologyAdult T-cell Leukemia-lymphomaCancer ResearchNt5c2 Germline VariantsHealth Sciences