Eculizumab Modifies Outcomes in Adults with Atypical Hemolytic Uremic Syndrome with Acute Kidney Injury

Mercedes Cao, Bruna N. Leite, Tamara Ferreiro, María Victoria Martínez Calvo, Constantino Fernández, Ángel Alonso, Alejandro Rodríguez, Pilar Salvador, Rocío Seijo, Salvador Pita,

American Journal of Nephrology · 2018 · 30 citations · 0 references

Abstract

Eculizumab shows greater efficacy than PE/PI alone for the treatment of adult aHUS patients with AKI. Prospective studies and meta-analyses are warranted to confirm our findings and set guidelines for treatment, monitoring, and maintenance.