The effects of methotrexate and hydroxychloroquine combination therapy<i>vs</i>methotrexate monotherapy in early rheumatoid arthritis patients

Abstract

In contrast to indirect comparison review data, MTX-HCQ seems somewhat more effective after 6 months than MTX monotherapy in early RA patients. After 12 months, we observed no significant differences between the two strategies, probably due to treat-to-target efforts.