Alcohol Intake Interacts with <i>CDKAL1</i>,<i> HHEX</i>, and <i>OAS3</i> Genetic Variants, Associated with the Risk of Type 2 Diabetes by Lowering Insulin Secretion in Korean Adults

Abstract

Subjects with a High-GRS had an elevated risk of T2DM even with moderate alcohol intakes due to lower HOMA-B. High alcohol intake appears to be a risk factor for all Asians regardless of alcohol intake.