Concepedia

Publication | Open Access

Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide

DOIFull Paper Access

68

Citations

33

References

2018

Year

Alex Shimura Yamashita, Marina da Costa Rosa, Alexandra Borodovsky, William T. Festuccia, Timothy A. Chan, Gregory J. Riggins
Neuro-Oncology

Abstract

5-Aza provided a survival benefit as a single agent but worked best in combination with TMZ in 2 different IDH1 R132H mutant glioma models.

References

YearCitations

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