The Laryngoscope · 2018 · 24 citations · 13 references
MedicinePlastic SurgerySurgeryPediatric Head SurgeryPediatric Oral SurgeryPediatric Plastic SurgeryFacial Plastic SurgeryPediatric MicrosurgeryCase Series ReviewFlap CreationNomaRetrospective Case AscertainmentRetrospective Case StudySurgical Procedure Description
OBJECTIVE: Noma is a devastating and destructive disease of the face for which there is a dearth of information regarding surgical options. Herein, we describe the facial deformities and patient characteristics in a patient population affected by noma and the surgical approaches used in treatment. METHODS: Retrospective case series of a Doctors Without Borders (Médecins Sans Frontières) intervention at Sokoto Children's Noma Hospital in northern Nigeria, the highest-volume noma hospital in the world. RESULTS: Twenty-two procedures were performed on 18 patients with noma, 44% of whom were children. The majority of patients (n = 10, 55.5%) were made aware of surgical care through a Doctors Without Borders outreach program. Patients' reasons for seeking care included functional (61.1%, n = 11), appearance (61.1%, n = 11), and social stigma (66.7%, n = 12). The majority (83.3%, n = 15) had lip involvement. Four patients (22.2%) underwent staged flap procedures including prelamination, flap delay, or pedicle division. The mean duration of surgical procedure was 87 minutes (range 5-306 minutes). The minor complication rate was 16%. There were no major complications or deaths. CONCLUSION: Noma is a mutilating disease of the face that occurs in settings of extreme malnutrition. A total of 55.5% of noma patients were made aware of surgical care through outreach programs. The majority of noma patients seek care to improve function (61.1%) and appearance (61.1%), and to address social stigma (66.7%). A total of 83.3% of noma patients had lip involvement. Facial reconstructive surgeons must rely on principles of congenital, traumatic, and oncologic deformity repair while focusing on safe, reliable procedures for low-resource settings. LEVEL OF EVIDENCE: 4 Laryngoscope, 129:96-99, 2019.
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EFFECT OF PSYCHOSOCIAL TREATMENT ON SURVIVAL OF PATIENTS WITH METASTATIC BREAST CANCER
David Spiegel, H C Kraemer, JoanR. Bloom et al. · The Lancet · 1989 · 2.4K citations
Medicine, Oncology, Psychology +12
Michael N. Tempest · British journal of surgery · 1966 · 148 citations
A History of Noma, the “Face of Poverty”
Klaas W. Marck · Plastic & Reconstructive Surgery · 2003 · 109 citations
Endocrine Dysfunction in Malignant Disease
Les Essex, E.A. Pask · The Lancet · 1964 · 88 citations
Medicine, Endocrinology, Oncology +14