Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF - Concepedia

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Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF

DOI Full Paper Access

78

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0

References

2018

Year

Dandan Zhong, Zhengwei Xie, Boyue Huang, Shuai Zhu, Guoqian Wang, Hong Zhou, Shuqian Lin, Zhibin Lin, Baoxue Yang

Cellular Physiology and Biochemistry

Abstract

GLPP significantly improves NAFLD via regulating bile acid synthesis dependent on FXR-SHP/FGF pathway, which finally inhibits fatty acid synthesis, indicating that GLPP might be developed as a therapeutic drug for NAFLD.