X-FaCT: Xenopus-Fast Clearing Technique

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin, Ignacio Arganda‐Carreras, Erwin Frise et al. · Nature Methods · 2012 · 70.9K citations

Engineering, Bioinformatics, Biology +9

Structural and molecular interrogation of intact biological systems

Kwanghun Chung, Jenelle L. Wallace, Sung‐Yon Kim et al. · Nature · 2013 · 2.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

Bin Yang, Jennifer B. Treweek, Rajan P. Kulkarni et al. · Cell · 2014 · 972 citations · Full text

Life Sciences, Biomedical Engineering, Cell Biology +15

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

Raju Tomer, Ye Li, Brian Hsueh et al. · Nature Protocols · 2014 · 867 citations · Full text

Engineering, Biomedical Engineering, Radiology +16

Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping

Jennifer B. Treweek, Ken Y. Chan, Nicholas C. Flytzanis et al. · Nature Protocols · 2015 · 274 citations

Engineering, Bioengineering, Biomedical Engineering +10