DNA nanoflower blooms in nanochannels: a new strategy for miRNA detection

Shi Liu, Chaoli Mu, Tao Gao, Tianshu Chen, Shuang Hei, Jie Yang, Genxi Li

Chemical Communications · 2018 · 43 citations · 16 references

Concepts

Abstract

By employing DNA nanoflower blooming in the nanochannels of porous anodic alumina (PAA), a nanochannel platform for microRNA (miRNA) detection has been proposed. Significant steric and electrostatic hindrance of the miRNA-initiated DNA-nanoflower growth may also amplify the signal readout for miRNA detection to give excellent sensitivity, selectivity and reproducibility.

References

16