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Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations

Medicinal ChemistryVirtual ScreeningPotent Prmt5 InhibitorsDrug TargetMedicineNatural SciencesRational Drug DesignMolecular BiologyStructural OptimizationDrug DevelopmentChemical BiologyPharmacologyDrug Discovery