Concepedia

Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake

Giuseppe D’Agostino, D. Lyons, Claudia Cristiano, Miriam Lettieri, Cristian M. Olarte‐Sánchez, Luke K. Burke, Megan Greenwald-Yarnell, Céline Cansell, Barbora Doslikova, Teodora Georgescu,

Cell Metabolism · 2018 · 148 citations · 34 references

DOIFull text

Open access

Concepts

Abstract

R agonist obesity medications require POMC within the NTS and ARC to reduce food intake.

References

34

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

Blaine N. Armbruster, Xiang Li, Mark H. Pausch et al. · Proceedings of the National Academy of Sciences · 2007 · 2.1K citations · Full text

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Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

Michael J. Krashes, Shuichi Koda, Chian-Ping Ye et al. · Journal of Clinical Investigation · 2011 · 1.6K citations · Full text

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Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Laurence H. Tecott, Linda M. Sun, Susan F. Akana et al. · Nature · 1995 · 1.3K citations

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AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

Deniz Atasoy, Scott M. Sternson · Nature Neuroscience · 2011 · 1.2K citations

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Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management

Steven R. Smith, Neil J. Weissman, Christen M. Anderson et al. · New England Journal of Medicine · 2010 · 912 citations · Full text

, , +17