Pneumologie · 2018 · 14 citations · 8 references
MedicineSurgeryCardiothoracic SurgeryEmergency SurgeryPulmonologyLung Resection SurgeryPleural SurgeryThoracic SurgeryConversion RatesIn-hospital MortalityMicrobiological CurePleural Disease SurgeryPleural Space ManagementSurgical Conversion RatesVideo-assisted Thoracic Surgery
OBJECTIVES: Evaluation of a standardised management for the treatment of patients with parapneumonic empyema. METHODS: A retrospective 10-year single-centre analysis of all patients with parapneumonic empyema undergoing a standardised thoracoscopic treatment approach. We describe referral and age patterns, microbiological results, overall and stage-dependent success rates, conversion rates, 30-day and in-hospital mortality. RESULTS: From May 2003 to April 2013, 248 patients with parapneumonic empyemas were treated in our centre. Most patients were referred at weekends, and younger patients had advanced stages. The cure rate in stage I was 97.6 % and reached 80.3 % in stage II and 63.1 % in stage III. 6 patients (2.4 %) (all stage III) needed conversion to an open procedure. A revision was required in 19.7 % of cases in stage II and 27.7 % in stage III. 30-day mortality was 4.8 %, in-hospital mortality was 8.1 %. CONCLUSION: A standardised approach, including VATS, is associated with a high cure, low revision and moderate conversion rates. In view of a still considerable mortality, a higher index of suspicion and detection of advanced stages, especially in younger patients, is required to improve outcomes.
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U.K. Controlled Trial of Intrapleural Streptokinase for Pleural Infection
Christopher W.H. Davies, Andrew Nunn, Emma Hedley et al. · New England Journal of Medicine · 2005 · 840 citations · Full text
Medicine, Pharmacotherapy, Surgery +16