The biofilm eradication activity of acetic acid in the management of periprosthetic joint infection

Abstract

This study found that the MBEC of acetic acid following a 10- or 20-minute treatment time exceeded its safety threshold, making these concentrations unsuitable as a topical debridement adjunct. However, a clinically acceptable concentration (5%) was still found to eliminate 96.1% of biofilm-associated MSSA following a 20-minute treatment time.<b>Cite this article</b>: S. T. J. Tsang, P. J. Gwynne, M. P. Gallagher, A. H. R. W. Simpson. The biofilm eradication activity of acetic acid in the management of periprosthetic joint infection. <i>Bone Joint Res</i> 2018;7:517-523. DOI: 10.1302/2046-3758.78.BJR-2018-0045.R1.