Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimer’s disease

Abstract

The fluorescence of functionalized NDs is more stable than that of fluorescent markers commonly used to stain Aβ aggregates such as Thioflavin T. These results pave the way for performing ultrasensitive and reliable detection of Aβ aggregates involved in the pathogenesis of the Alzheimer disease.