An analysis of blastic plasmacytoid dendritic cell neoplasm with translocations involving the <i><scp>MYC</scp></i> locus identifies t(6;8)(p21;q24) as a recurrent cytogenetic abnormality

Abstract

Translocations involving the 8q24 MYC locus more frequently manifest as t(6;8)(p21;q24), and, given its association with specific clinicopathological features suggesting even more aggressive behaviour, t(6;8)(p21;q24) indicate a genetically defined subgroup within BPDCN.