Concepedia

Discovery and Identification of an Endogenous Metabolite of Tramiprosate and Its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation in the Human Brain

John A. Hey, Petr Kočiš, Jakub Hort, Susan Abushakra, Aidan Power, Martin Vyhnálek, Yongxin Yu, Martin Tolar

CNS Drugs · 2018 · 70 citations · 26 references

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References

26

Principles of biochemistry

Biochemical Education · 1978 · 5.1K citations

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Diffusible, nonfibrillar ligands derived from Aβ <sub>1–42</sub> are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

Jeff Sevigny, Ping Chiao, Thierry Bussière et al. · Nature · 2016 · 3K citations

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Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

Leslie M. Shaw, Hugo Vanderstichele, Małgorzata Knapik-Czajka et al. · Annals of Neurology · 2009 · 2.1K citations · Full text

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

Stephen Salloway, Reisa A. Sperling, Nick C. Fox et al. · New England Journal of Medicine · 2014 · 1.9K citations · Full text