Journal of Proteome Research · 2018 · 37 citations · 18 references
Life SciencesBiochemistryBioinformaticsProtein BiochemistryProteomicsProteomics InformaticsClinical ProteomicsMass Spectrometry Data AnalysisMass Spectrometry-based ProteomicsProtein IdentificationCerebrospinal Fluid Protein StudiesGel ElectrophoresisLinear Ion Trap Mass AnalyzersProtein Analysis In Body FluidsProteome AnnotationProteome BioinformaticsProteomic Biomarker ValidationProteomic Data Analysis
The cerebrospinal fluid (CSF) proteome data set presented herein was obtained after immunodepletion of abundant proteins and off-gel electrophoresis fractionation of a commercial pool of normal human CSF; liquid chromatography tandem mass spectrometry analysis was performed with a linear ion trap-Orbitrap Elite. We report the identification of 12 344 peptides mapping on 2281 proteins. In the context of the Chromosome-centric Human Proteome Project (C-HPP), the existence of seven missing proteins is proposed to be validated. This data set is available to the ProteomeXchange Consortium ( http://www.proteomexchange.org/ ) with the data set identifier PXD008029.
18