Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle

A simple and sensitive saturation assay method for the measurement of adenosine 3′:5′-cyclic monophosphate

B. L. Brown, J. D. M. Albano, Roger Ekins et al. · Biochemical Journal · 1971 · 1.5K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

Conformational biosensors reveal GPCR signalling from endosomes

Roshanak Irannejad, Jin C. Tomshine, Jon R. Tomshine et al. · Nature · 2013 · 840 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor

Sudha K. Shenoy, Matthew T. Drake, Christopher Nelson et al. · Journal of Biological Chemistry · 2005 · 756 citations · Full text

Life Sciences, Pharmacology, Physiology +16

Distinct Phosphorylation Sites on the β ₂ -Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin

Kelly N. Nobles, Kunhong Xiao, Seungkirl Ahn et al. · Science Signaling · 2011 · 625 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

The selectivity of <i>β</i>‐adrenoceptor antagonists at the human <i>β</i>1, <i>β</i>2 and <i>β</i>3 adrenoceptors

Jillian G. Baker · British Journal of Pharmacology · 2005 · 535 citations · Full text

Medicine, Cardiology, Pharmacology +14