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Knockout of CNR1 prevents metabolic stress-induced cardiac injury through improving insulin resistance (IR) injury and endoplasmic reticulum (ER) stress by promoting AMPK-alpha activation

Insulin ResistanceMetabolic SyndromeAmpk-alpha ActivationHeart FailureMolecular PhysiologyHealth SciencesCardiomyopathyInsulin SignalingPhysiologyDiabetesMetabolic RegulationMetabolic RemodelingMedicineCell BiologyCell SignalingOxidative StressEndoplasmic Reticulum