[18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18 kDa)

A General Copper‐Mediated Nucleophilic ¹⁸F Fluorination of Arenes

Matthew Tredwell, Sean Preshlock, Nicholas J. Taylor et al. · Angewandte Chemie International Edition · 2014 · 379 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

Christine Sandiego, Jean‐Dominique Gallezot, Brian Pittman et al. · Proceedings of the National Academy of Sciences · 2015 · 349 citations · Full text

Medicine, Neurobiology, Neuroscience +17

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease

William Charles Kreisl, Chul Hyoung Lyoo, Meghan McGwier et al. · Brain · 2013 · 348 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics

Benjamin H. Rotstein, Nickeisha A. Stephenson, Neil Vasdev et al. · Nature Communications · 2014 · 241 citations · Full text

Natural Sciences, Chemistry, Organic Chemistry +2

Increased Binding of Peripheral Benzodiazepine Receptor in Alzheimer's Disease Measured by Positron Emission Tomography with [11C]DAA1106

Fumihiko Yasuno, Miho Ota, Jun Kosaka et al. · Biological Psychiatry · 2008 · 215 citations · Full text

Medicine, Neuroscience, Pharmacology +12