Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

Walter Halangk, Markus M. Lerch, Barbara Brandt-Nedelev et al. · Journal of Clinical Investigation · 2000 · 566 citations · Full text

Medicine, Pathobiology, Pathology +14

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models

György Biczó, Eszter T. Végh, Natalia Shalbueva et al. · Gastroenterology · 2017 · 420 citations · Full text

Life Sciences, Cell Biology, Pathobiology +17

Intra-acinar Trypsinogen Activation Mediates Early Stages of Pancreatic Injury but Not Inflammation in Mice With Acute Pancreatitis

Rajinder Dawra, Raghuwansh P. Sah, Vikas Dudeja et al. · Gastroenterology · 2011 · 252 citations · Full text

Veterinary Medicine, Cell Biology, Pathobiology +11

Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis

Matthias Sendler, Sandrina Maertin, Daniel John et al. · Journal of Biological Chemistry · 2016 · 134 citations · Full text

Life Sciences, Cell Biology, Pathology +17

Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis

Rupjyoti Talukdar, Archana Sareen, Hongyan Zhu et al. · Gastroenterology · 2016 · 123 citations · Full text

Life Sciences, Biochemistry, Cell Biology +10