Sevoflurane affects neurogenesis through cell cycle arrest via inhibiting wnt/β-catenin signaling pathway in mouse neural stem cells

Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

Vesna Jevtović‐Todorović, Richard E. Hartman, Yukitoshi Izumi et al. · Journal of Neuroscience · 2003 · 2K citations · Full text

Medicine, Anesthesiology, Neuroscience +17

Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial

Andrew Davidson, Nicola Disma, Jurgen C. de Graaff et al. · The Lancet · 2015 · 1.1K citations · Full text

Medicine, Anesthesiology, Pediatrics +15

Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood

Lena S. Sun, Guohua Li, Tonya Miller et al. · JAMA · 2016 · 945 citations

Medicine, Child Health, Pediatrics +13

Cognitive and Behavioral Outcomes After Early Exposure to Anesthesia and Surgery

Randall P. Flick, Slavica K. Katusic, Robert C. Colligan et al. · PEDIATRICS · 2011 · 899 citations · Full text

Medicine, Anesthesiology, Surgery +14

Cdk4/CyclinD1 Overexpression in Neural Stem Cells Shortens G1, Delays Neurogenesis, and Promotes the Generation and Expansion of Basal Progenitors

Christian Lange, Wieland Β. Huttner, Federico Calegari · Cell stem cell · 2009 · 577 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +12