Publication | Open Access
Multienzyme One-Pot Cascade for the Stereoselective Hydroxyethyl Functionalization of Substituted Phenols
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Citations
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References
2018
Year
EngineeringSubstrate ScopeOrganic ChemistryChemistryNovel OrganocatalystsSubstituted PhenolsSustainable SynthesisMultienzyme One-pot CascadeStereoselective SynthesisRedesigned Vinylphenol HydrataseCoumaric AcidsStereoselective Hydroxyethyl FunctionalizationBiochemistryBiocatalysisCatalysisAsymmetric CatalysisEnantioselective SynthesisCatalytic SynthesisBiomolecular EngineeringNatural SciencesEnzyme CatalysisMolecular CatalysisSynthetic Chemistry
The operability and substrate scope of a redesigned vinylphenol hydratase as a single biocatalyst or as part of multienzyme cascades using either substituted coumaric acids or phenols as stable, cheap, and readily available substrates are reported.
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