Potential Diagnosis of Vitreoretinal Lymphoma by Detection of<i>MYD88</i>Mutation in Aqueous Humor With Ultrasensitive Droplet Digital Polymerase Chain Reaction

Abstract

The high concordance between aqueous humor and vitreous fluid samples suggests that use of the easily accessible aqueous humor is nearly as informative as vitreous fluid in the identification of key somatic mutations in patients with VRL. This approach may provide an additional minimally invasive tool for accurate diagnosis, detection of recurrence, and monitoring of treatment.